Ewing’s Sarcoma intra-vital drug testing

Already funded by the Rutledge and Sam Day Foundations

We have developed an inexpensive, time-saving replacement for mouse drug testing using quail eggs. What could take 10 weeks and $45,000 in mouse studies would take 10-11 days and only 35 cents per egg. However, we want to preserve tumor tissue architecture, too. Much to our surprise, we were able to grow a slice of an autopsy-derived Ewing’s sarcoma tumor on the CAM membrane. What remains to be done is to optimize the tumor slice placement, and develop a method to test if a drug kills the tumor cells in the slice.