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Our team is on a mission to make childhood cancer universally survivable!
The FDA approves on average 12 drugs every year to treat adult cancer, but has only approved 10 drugs to treat childhood cancer since 1978 (10 in 44 years for kids).
Since our inception in 2015, cc-TDI has pushed two drugs into three clinical trials to treat childhood cancer.
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Newly Published Studies Suggest a Framework for RMS Drug Development
We are thrilled to announce a new publication, Structure-activity relationship of dihydropyridines for rhabdomyosarcoma, showcasing results of a study of a massive drug & chemical screen for the childhood muscle cancer, rhabdomyosarcoma (RMS), in the journal Biochemical and Biophysical Research Communications. Rhabdomyosarcoma (RMS) is the most common soft tissue tumor in children with approximately 400 cases detected per year in the United States. The World Health Organization recognizes three major categories of RMS based on histological features, i.e., alveolar, embryonal, pleomorphic and spindle cell sclerosing RMS. Alveolar and embryonal RMS are the most common types
In the Press
Beaverton lab identifies drug that turns off key gene in deadly childhood muscle cancer
The Children's Cancer Therapy Development Institute is studying how a breast cancer drug candidate could impact children with an aggressive tumor in the soft muscle.
Scientists And Parents Band Together To Research Cures For Rare Childhood Cancer
Small patient numbers mean there's less motivation to allocate resources to study the diseases and develop potential drugs. Dozens of childhood cancers fall in this category, some so rare that few pediatric oncologists hear about them.
Beaverton's Children's Cancer Therapy Development Institute tackles deadliest child cancers
Beyond an unmarked door into what looks like a shabby old warehouse in Old Town Beaverton, white-coated scientists are working to find ways to treat cancers that kill almost every child they afflict.
Current Research Projects
A dedicated research team
Our research team is exploring and testing state-of-the-art treatment options for the most urgent issues facing children with cancer.
Working in our own freestanding research institution allows us to act swiftly and nimbly to achieve results—bringing cost control, speed, purpose, and focus to translate effective treatments into the clinic. To get there, we perform basic science and translational research in our industrial modern lab site (a paint factory remodeled by Nike as an off-site creative space), adjacent to the Silicon Forest in Oregon.